FAAH/MAGL-IN-3 is an irreversible inhibitor targeting fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) with IC50 values of 179 nM and 759 nM, respectively. This dual inhibitor is valuable for studying endocannabinoid metabolism and its implications in various physiological and pathological processes. Notably, FAAH/MAGL-IN-3 demonstrates low permeability in the PAMPA assay, indicating a potential for selective activity in research applications.
FAAH/MAGL-IN-3 is an irreversible inhibitor targeting fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) with IC50 values of 179 nM and 759 nM, respectively. This dual inhibitor is valuable for studying endocannabinoid metabolism and its implications in various physiological and pathological processes. Notably, FAAH/MAGL-IN-3 demonstrates low permeability in the PAMPA assay, indicating a potential for selective activity in research applications.
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