FG-4592 (Roxadustat)

FG-4592 is a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia.
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Product Name Price Stock Qty
FG-4592 10mg
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FG-4592 50mg
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FG-4592 100mg
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FG-4592 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's FG-4592 (Roxadustat) has been cited by 5 publications
  • Weilin Song, .et al. , Biomedicines, 2022, Dec 23;11(1):37 PMID: 36672545
  • Singh C, .et al. , JCI Insight, 2019, Jul 25;4(14) PMID: 31341109
  • Hideaki Nakamura, .et al. , PLoS One, 2018, 13(2): e0192136 PMID: 29466367
  • Singh C, .et al. , Invest Ophthalmol Vis Sci, 2018, Jul 2;59(8):3440-3448 PMID: 30025089
  • George Hoppe, .et al. , Proc Natl Acad Sci U S A, 2016, May 3; 113(18): E2516-E2525 PMID: 27091985
  • Biological Activity
    Discription FG-4592 is a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia.
    Target Value
    Product Information
    Catalog Num A11237
    Formula C19H16N2O5
    Molecular Weight 352.3
    CAS Number 808118-40-3
    Synonyms FG4592, ASP1517

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 62 mg/mL (175.96 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.38 mL 141.92 mL 283.85 mL
    0.5 mM 5.68 mL 28.38 mL 56.77 mL
    1 mM 2.84 mL 14.19 mL 28.38 mL
    5 mM 0.57 mL 2.84 mL 5.68 mL
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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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