Filaminast

Catalog No.: A42165
PDE-IV Inhibitor
Filaminast is a selective phosphodiesterase type IV (PDE-IV) inhibitor, exhibiting an IC50 of 0.42 μM against canine trachealis PDE-IV. This compound promotes respiratory muscle relaxation and induces bronchodilation, making it a valuable tool for research in respiratory disorders and inflammation-related studies. Its mechanism of action facilitates the modulation of intracellular signaling pathways associated with airway constriction, contributing to potential therapeutic applications in respiratory diseases.
Grouped product items
Size Price Stock Qty
1mg
$135.00
In stock
5mg
$335.00
In stock
10mg
$455.00
In stock
25mg
$690.00
In stock
50mg
$895.00
In stock
100mg
$1,175.00
In stock
200mg
$1,550.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFilaminast is a selective phosphodiesterase type IV (PDE-IV) inhibitor, exhibiting an IC50 of 0.42 μM against canine trachealis PDE-IV. This compound promotes respiratory muscle relaxation and induces bronchodilation, making it a valuable tool for research in respiratory disorders and inflammation-related studies. Its mechanism of action facilitates the modulation of intracellular signaling pathways associated with airway constriction, contributing to potential therapeutic applications in respiratory diseases.
Product Information
Catalog NumA42165
FormulaC15H20N2O4
Molecular Weight292.33
CAS Number141184-34-1
SMILESC/C(C1=CC=C(OC)C(OC2CCCC2)=C1)=N\OC(N)=O
SynonymsWAY-PDA 641
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