Fipronil sulfone is a primary metabolite of the insecticide Fipronil, acting as a selective antagonist of GABA receptors. With an IC50 value of 175 nM, it effectively inhibits GABA receptor-mediated neurotransmission by displacing [3H]EBOB from its noncompetitive blocker site. This compound is important for research into neurotoxicology and the study of insect neurobiology.
Fipronil sulfone is a primary metabolite of the insecticide Fipronil, acting as a selective antagonist of GABA receptors. With an IC50 value of 175 nM, it effectively inhibits GABA receptor-mediated neurotransmission by displacing [3H]EBOB from its noncompetitive blocker site. This compound is important for research into neurotoxicology and the study of insect neurobiology.
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