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$0.00 - Higuchi S, .et al. Inhibition of the integrin signal constitutes a mouse iPS cell niche, Dev Growth Differ, 2016, Sep;58(7):586-99 PMID: 27633818
Biological Activity
Firategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.02 mL | 100.1 mL | 200.2 mL |
| 0.5 mM | 4 mL | 20.02 mL | 40.04 mL |
| 1 mM | 2 mL | 10.01 mL | 20.02 mL |
| 5 mM | 0.4 mL | 2 mL | 4 mL |
*The above data is based on the productmolecular weight 499.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12787 |
|---|---|
| Actions | Antagonist |
| M. Wt | 499.51 |
| Formula | C27H27F2NO6 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 402567-16-2 |
| Synonyms | SB-683699, SB683699 |
| SMILES | CCOCC1=CC(=C(C(=C1)OC)C2=CC=C(C=C2)C[[email protected]@H](C(=O)O)NC(=O)C3=C(C=CC=C3F)F)OC |
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