FK866

Catalog No.: A11279

NMPRTase Inhibitor

FK866

FK866 Chemical Structure

CAS NO. 658084-64-1

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.

Availability: In stock

Package Price Qty
10 mg
$100.00
25 mg
$240.00
50 mg
$380.00
100 mg
$640.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Targets
NMPRTase (Cell-free assay)
0.09 nM
In vitro (25°C) DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 78 mg/mL (199.22 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.54 mL 127.71 mL 255.43 mL
0.5 mM 5.11 mL 25.54 mL 51.09 mL
1 mM 2.55 mL 12.77 mL 25.54 mL
5 mM 0.51 mL 2.55 mL 5.11 mL

*The above data is based on the productmolecular weight 391.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11279
Actions Inhibitor
M. Wt 391.5
Formula C24H29N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 658084-64-1
Synonyms K 22.175, FK-866
SMILES C1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3

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