FK866

Catalog No.: A11279
NMPRTase Inhibitor
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
5mg
$50.00
In stock
10mg
$90.00
In stock
25mg
$190.00
In stock
50mg
$375.00
In stock
100mg
$580.00
In stock
500mg
$1,225.00
In stock
10mM * 1mL in DMSO
$55.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Adooq's FK866 has been cited by 6 publications
  • T Nakajo, .et al. , Biochem Biophys Res Commun, 2024, Oct 30:731:150371 PMID: 39004065
  • Takeshi Katayoshi, .et al. , Sci Rep, 2022, Nov 9;12(1):19040 PMID: 36352014
  • Takeshi Nakamura, .et al. , Shimane Journal of Medical Science, 2022, 38 (2), 59-66
  • Takeshi Katayoshi, .et al. , J Photochem Photobiol B, 2021, Jun 12;221:112238 PMID: 34130091
  • Yool Lee, .et al. , Sci Adv, 2021, 7
  • Peter M LoCoco, .et al. , eLife, 2017, 6: e29626 PMID: 29125463
  • Biological Activity
    Discription FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11279
    Formula C24H29N3O2
    Molecular Weight 391.5
    CAS Number 658084-64-1
    SMILES C1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3
    Synonyms K 22.175, FK-866
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Insoluble
    Water Insoluble
    Ethanol 77 mg/mL (196.67 mM)
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O 3 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.54 mL 127.71 mL 255.43 mL
    0.5 mM 5.11 mL 25.54 mL 51.09 mL
    1 mM 2.55 mL 12.77 mL 25.54 mL
    5 mM 0.51 mL 2.55 mL 5.11 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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