FK866

Catalog No.: A11279
NMPRTase Inhibitor
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
5mg
$50.00
In stock
10mg
$90.00
In stock
25mg
$190.00
In stock
50mg
$375.00
In stock
100mg
$580.00
In stock
500mg
$1,225.00
In stock
10mM * 1mL in DMSO
$55.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Adooq's FK866 has been cited by 6 publications
  • T Nakajo, .et al. , Biochem Biophys Res Commun, 2024, Oct 30:731:150371 PMID: 39004065
  • Takeshi Katayoshi, .et al. , Sci Rep, 2022, Nov 9;12(1):19040 PMID: 36352014
  • Takeshi Nakamura, .et al. , Shimane Journal of Medical Science, 2022, 38 (2), 59-66
  • Takeshi Katayoshi, .et al. , J Photochem Photobiol B, 2021, Jun 12;221:112238 PMID: 34130091
  • Yool Lee, .et al. , Sci Adv, 2021, 7
  • Peter M LoCoco, .et al. , eLife, 2017, 6: e29626 PMID: 29125463
Biological Activity
DescriptionFK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Targets
TargetValue
Cell Research
Cell LineTypeValueDescriptionReferences
Product Information
Catalog NumA11279
FormulaC24H29N3O2
Molecular Weight391.5
CAS Number658084-64-1
SMILESC1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3
SynonymsK 22.175, FK-866
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSOInsoluble
WaterInsoluble
Ethanol77 mg/mL (196.67 mM)
In vivo5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.54 mL127.71 mL255.43 mL
0.5 mM5.11 mL25.54 mL51.09 mL
1 mM2.55 mL12.77 mL25.54 mL
5 mM0.51 mL2.55 mL5.11 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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