FLT3-IN-32 TFA is a selective inhibitor of FLT3, targeting both FLT3-ITD and FLT3-D835Y with IC50 values of 2.40 nM and 3.83 nM, respectively. This compound effectively inhibits the proliferation and survival of human MV4-11 cells, demonstrating an IC50 of 0.07 nM. FLT3-IN-32 TFA is valuable for research focused on acute myeloid leukemia (AML), providing insights into targeted therapeutic strategies.
FLT3-IN-32 TFA is a selective inhibitor of FLT3, targeting both FLT3-ITD and FLT3-D835Y with IC50 values of 2.40 nM and 3.83 nM, respectively. This compound effectively inhibits the proliferation and survival of human MV4-11 cells, demonstrating an IC50 of 0.07 nM. FLT3-IN-32 TFA is valuable for research focused on acute myeloid leukemia (AML), providing insights into targeted therapeutic strategies.
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