Flucytosine is an antifungal used in the treatment of severe candidal and cryptococcal infections. It converted to fluorouracil after entering fungi, which inhibits DNA and RNA synthesis
Flucytosine is an antifungal used in the treatment of severe candidal and cryptococcal infections. It converted to fluorouracil after entering fungi, which inhibits DNA and RNA synthesis
Product Information
Catalog Num
A10394
Formula
C4H4FN3O
Molecular Weight
129.1
CAS Number
2022-85-7
SMILES
C1=NC(=O)NC(=C1F)N
Synonyms
5-fluorocytosine, Ancotil
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
7 mg/mL (54.22 mM)
Water
4 mg/mL (30.98 mM)
Ethanol
Insoluble
In vivo
0.5% methylcellulose+0.2% Tween 80
4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: