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Publications citing Adooq Products
Chemical Information
| Catalog Num | A10394 |
|---|---|
| Actions | N/A |
| M. Wt | 129.1 |
| Formula | C4H4FN3O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2022-85-7 |
| Synonyms | 5-fluorocytosine, Ancotil |
| SMILES code | C1=NC(=O)NC(=C1F)N |
| Chemical Name | 4-amino-5-fluoro-1,2-dihydropyrimidin-2-one |
Description |
Flucytosine is an antifungal used in the treatment of severe candidal and cryptococcal infections. It converted to fluorouracil after entering fungi, which inhibits DNA and RNA synthesis | ||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 8 mg/mL (61.97 mM) |
|---|---|---|---|
| Water | 5 mg/mL (38.73 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 0.5% methylcellulose/0.2% Tween 80 | 5 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 77.46 mL | 387.3 mL | 774.59mL |
| 0.5 mM | 15.49 mL | 77.46 mL | 154.92 mL |
| 1 mM | 7.75 mL | 38.73 mL | 77.46 mL |
| 5 mM | 1.55 mL | 7.75 mL | 15.49 mL |
*The above data is based on the productmolecular weight 129.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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