fluoro-Dapagliflozin

Catalog No.: A68420
SGLT2 Inhibitor
Fluoro-Dapagliflozin is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, exhibiting a Ki value of 5.3 nM for SGLT2 and 330 nM for SGLT1. It functions by blocking glucose transport, thereby reducing glucose absorption in the kidneys. This compound is valuable for research applications aimed at understanding glucose homeostasis, diabetic metabolism, and the therapeutic potential in managing type 2 diabetes.
Grouped product items
Size Price Stock Qty
1mg
$85.00
In stock
5mg
$215.00
In stock
10mg
$410.00
In stock
25mg
$900.00
In stock
50mg
$1,495.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFluoro-Dapagliflozin is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, exhibiting a Ki value of 5.3 nM for SGLT2 and 330 nM for SGLT1. It functions by blocking glucose transport, thereby reducing glucose absorption in the kidneys. This compound is valuable for research applications aimed at understanding glucose homeostasis, diabetic metabolism, and the therapeutic potential in managing type 2 diabetes.
Product Information
Catalog NumA68420
FormulaC21H24ClFO5
Molecular Weight410.86
CAS Number1181681-43-5
SMILESO[C@H]1[C@H](C2=CC(CC3=CC=C(C=C3)OCC)=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)F)CO
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