Fmoc-NH-PEG4-CH2CH2COOH

Catalog No.: A42554
ADC Linker
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable linker designed for antibody-drug conjugates (ADCs), facilitating the targeted delivery of cytotoxic agents to cancer cells. This compound serves as a PEG-based PROTAC linker, enabling the construction of proteolysis-targeting chimeras (PROTACs) for efficient degradation of specific proteins in various biological contexts. It is suitable for applications in drug development and biochemical research, particularly in the fields of oncology and targeted therapeutics.
Grouped product items
Size Price Stock Qty
100mg
$25.00
In stock
250mg
$40.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFmoc-NH-PEG4-CH2CH2COOH is a cleavable linker designed for antibody-drug conjugates (ADCs), facilitating the targeted delivery of cytotoxic agents to cancer cells. This compound serves as a PEG-based PROTAC linker, enabling the construction of proteolysis-targeting chimeras (PROTACs) for efficient degradation of specific proteins in various biological contexts. It is suitable for applications in drug development and biochemical research, particularly in the fields of oncology and targeted therapeutics.
Product Information
Catalog NumA42554
FormulaC26H33NO8
Molecular Weight487.54
CAS Number557756-85-1
SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCC(O)=O
SynonymsFmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2