FPPQ

Catalog No.: A29641
5-HT3/6 Receptor Antagonist
FPPQ is a dual-acting antagonist of the 5-HT3 and 5-HT6 receptors, demonstrating high affinity with Ki values of 0.9 nM and 3 nM, respectively. This compound exhibits significant antipsychotic and procognitive effects, making it a valuable tool for research into neuropsychiatric disorders. Its ability to modulate serotonergic signaling positions FPPQ as a promising candidate for studies focused on cognitive enhancement and the treatment of mental health conditions.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFPPQ is a dual-acting antagonist of the 5-HT3 and 5-HT6 receptors, demonstrating high affinity with Ki values of 0.9 nM and 3 nM, respectively. This compound exhibits significant antipsychotic and procognitive effects, making it a valuable tool for research into neuropsychiatric disorders. Its ability to modulate serotonergic signaling positions FPPQ as a promising candidate for studies focused on cognitive enhancement and the treatment of mental health conditions.
Product Information
Catalog NumA29641
FormulaC21H19FN4O2S
Molecular Weight410.46
CAS Number1648745-46-3
SMILESO=S(N1C=CC2=C1C3=CC=CC=C3N=C2N4CCNCC4)(C5=CC(F)=CC=C5)=O
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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