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Fulvestrant (Faslodex)

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Aromatase inhibitor

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Catalog No. A10410

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Fulvestrant 25mg A10410-25

Regular Price: $50.00

Special Price: $45.00

Fulvestrant 50mg A10410-50

Regular Price: $70.00

Special Price: $63.00

Fulvestrant 100mg A10410-100

Regular Price: $100.00

Special Price: $90.00

Fulvestrant 200mg A10410-200

Regular Price: $350.00

Special Price: $315.00

Fulvestrant (Faslodex) 10mM * 1mL in DMSO A10410-10mM-D

Regular Price: $55.00

Special Price: $49.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Fulvestrant is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

Fulvestrant (Faslodex)

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Publications citing Adooq Products
Fulvestrant (Faslodex) Citations (5)
  • Samy A. F. Morad, .et al. Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer, Biochem Pharmacol, 2017, Apr 15; 130: 21-33 PMID: 28189725
  • Kaneyasu Nishimura, .et al. Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α5β1, Stem Cell Reports, 2016, Apr 12; 6(4): 511-524 PMID: 26997644
  • Alejandro S. Cazzulino, .et al. Improved specificity of hippocampal memory trace labeling, Hippocampus, 2016, Jun; 26(6): 752-762 PMID: 26662713
  • Rie Mukai, .et al. 8-Prenylnaringenin promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice, Am J Physiol Regul Integr Comp Physiol, 2016, Dec 1;311(6):R1022-R1031 PMID: 27629889
  • Sakanashi M, .et al. Long-term treatment with san'o-shashin-to, a kampo medicine, markedly ameliorates cardiac ischemia-reperfusion injury in ovariectomized rats via the redox-dependent mechanism., Circ J. , 2013, 77(7):1827-37. PMID: 23615023

Chemical Information

Catalog Num A10410
Actions Inhibitor
M. Wt 606.8
Formula C32H47F5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 129453-61-8
Synonyms ICI 182,780 ; ICI 182780 ; ICI182780
SMILES C[[email protected]]12CC[[email protected]]3[[email protected]]([[email protected]@H]1CC[[email protected]@H]2O)[[email protected]@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F

Biological Activity

Description
Fulvestrant is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.
Targets
ER (Cell-free assay)
0.94 nM

Solubility

Solubility (25°C) * In vitro DMSO 100 mg/mL (164.8 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (164.8 mM)
In vivo 5% DMSO/95% Corn oil 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.48 mL 82.4 mL 164.8mL
0.5 mM 3.3 mL 16.48 mL 32.96 mL
1 mM 1.65 mL 8.24 mL 16.48 mL
5 mM 0.33 mL 1.65 mL 3.3 mL

*The above data is based on the productmolecular weight 606.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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