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- Samy A. F. Morad,et al. Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer, Biochem Pharmacol, 2017, Apr 15; 130: 21-33 28189725
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|Storage||at -20°C 3 years Powder|
|Synonyms||ICI 182,780 ; ICI 182780 ; ICI182780|
|SMILES code||C[[email protected]]12CC[[email protected]]3[[email protected]]([[email protected]@H]1CC[[email protected]@H]2O)[[email protected]@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F|
|Fulvestrant is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.|
|Solubility (25°C) *||In vitro||DMSO||100 mg/mL (164.8 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||100 mg/mL (164.8 mM)|
|In vivo||5% DMSO/95% Corn oil||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||16.48 mL||82.4 mL||164.8mL|
|0.5 mM||3.3 mL||16.48 mL||32.96 mL|
|1 mM||1.65 mL||8.24 mL||16.48 mL|
|5 mM||0.33 mL||1.65 mL||3.3 mL|
*The above data is based on the productmolecular weight 606.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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