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- Samy A. F. Morad, .et al. Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer, Biochem Pharmacol, 2017, Apr 15; 130: 21-33 PMID: 28189725
- Kaneyasu Nishimura, .et al. Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α5β1, Stem Cell Reports, 2016, Apr 12; 6(4): 511-524 PMID: 26997644
- Alejandro S. Cazzulino, .et al. Improved specificity of hippocampal memory trace labeling, Hippocampus, 2016, Jun; 26(6): 752-762 PMID: 26662713
- Rie Mukai, .et al. 8-Prenylnaringenin promotes recovery from immobilization-induced disuse muscle atrophy through activation of the Akt phosphorylation pathway in mice, Am J Physiol Regul Integr Comp Physiol, 2016, Dec 1;311(6):R1022-R1031 PMID: 27629889
- Sakanashi M, .et al. Long-term treatment with san'o-shashin-to, a kampo medicine, markedly ameliorates cardiac ischemia-reperfusion injury in ovariectomized rats via the redox-dependent mechanism., Circ J. , 2013, 77(7):1827-37. PMID: 23615023
|Storage||at -20°C 3 years Powder|
|Synonyms||ICI 182,780 ; ICI 182780 ; ICI182780|
|SMILES||C[[email protected]]12CC[[email protected]]3[[email protected]]([[email protected]@H]1CC[[email protected]@H]2O)[[email protected]@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F|
|Fulvestrant is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.|
|Solubility (25°C) *||In vitro||DMSO||100 mg/mL (164.8 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||100 mg/mL (164.8 mM)|
|In vivo||5% DMSO/95% Corn oil||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||16.48 mL||82.4 mL||164.8mL|
|0.5 mM||3.3 mL||16.48 mL||32.96 mL|
|1 mM||1.65 mL||8.24 mL||16.48 mL|
|5 mM||0.33 mL||1.65 mL||3.3 mL|
*The above data is based on the productmolecular weight 606.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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