FXR Agonist 11 is a selective agonist of the farnesoid X receptor (FXR) with an EC50 of 1.2 μM and a maximum biological effect of 73.7%. This compound significantly elevates glutathione (GSH) levels in liver tissues, making it a valuable tool for investigating mechanisms of drug-induced liver injury and related hepatic disorders. Research applications include studies of metabolic regulation, liver protection, and the modulation of hepatic stress responses.
FXR Agonist 11 is a selective agonist of the farnesoid X receptor (FXR) with an EC50 of 1.2 μM and a maximum biological effect of 73.7%. This compound significantly elevates glutathione (GSH) levels in liver tissues, making it a valuable tool for investigating mechanisms of drug-induced liver injury and related hepatic disorders. Research applications include studies of metabolic regulation, liver protection, and the modulation of hepatic stress responses.
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