GABAA receptor agent 5 is a selective antagonist of the γ-GABAAR, exhibiting a high binding affinity with a Ki value of 0.020 µM. This compound demonstrates effective γ-GABAAR antagonistic activity while maintaining low cellular membrane permeability. It serves as a valuable tool for research investigating the roles of γ-GABAAR in neurological disorders and synaptic transmission studies.
GABAA receptor agent 5 is a selective antagonist of the γ-GABAAR, exhibiting a high binding affinity with a Ki value of 0.020 µM. This compound demonstrates effective γ-GABAAR antagonistic activity while maintaining low cellular membrane permeability. It serves as a valuable tool for research investigating the roles of γ-GABAAR in neurological disorders and synaptic transmission studies.
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