GABAA receptor agent 6 is a potent antagonist of the γ-GABAAR, exhibiting an inhibition constant (Ki) of 0.56 µM. This compound demonstrates significant γ-GABAAR antagonistic activity while maintaining low permeability across cellular membranes. It is suitable for research applications involving the investigation of GABAergic signaling and the modulation of inhibitory neurotransmission in various biological systems.
GABAA receptor agent 6 is a potent antagonist of the γ-GABAAR, exhibiting an inhibition constant (Ki) of 0.56 µM. This compound demonstrates significant γ-GABAAR antagonistic activity while maintaining low permeability across cellular membranes. It is suitable for research applications involving the investigation of GABAergic signaling and the modulation of inhibitory neurotransmission in various biological systems.
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