GABAA receptor modulator-2 is a selective negative allosteric modulator of the α5-GABAAR with a Ki of 4.1 nM. This orally active compound demonstrates high metabolic stability and favorable safety profiles in the central nervous system. It is valuable for research focusing on GABAergic signaling and its implications in various neurological conditions.
GABAA receptor modulator-2 is a selective negative allosteric modulator of the α5-GABAAR with a Ki of 4.1 nM. This orally active compound demonstrates high metabolic stability and favorable safety profiles in the central nervous system. It is valuable for research focusing on GABAergic signaling and its implications in various neurological conditions.
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