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GABAA receptor modulator-8

Catalog No.: A66910
GABAA Receptor Modulator
GABAA receptor modulator-8 is a selective positive modulator of the GABAA receptor, designed for effective penetration of the blood-brain barrier. This compound exhibits significant antiepileptic activity, making it a valuable tool for research into neurological disorders. Its unique properties support studies aimed at understanding GABAA receptor interactions and their therapeutic potential in epilepsy and related conditions.
GABAA receptor modulator-8 2889382-34-5 GABAA Receptor Modulator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGABAA receptor modulator-8 is a selective positive modulator of the GABAA receptor, designed for effective penetration of the blood-brain barrier. This compound exhibits significant antiepileptic activity, making it a valuable tool for research into neurological disorders. Its unique properties support studies aimed at understanding GABAA receptor interactions and their therapeutic potential in epilepsy and related conditions.
Product Information
Catalog NumA66910
FormulaC20H17FN4O
Molecular Weight348.37
CAS Number2889382-34-5
SMILESCCCOC1=CC(C2=CC=CC=C2)=NC3=NC(C4=C(F)C=CC=C4)=NN13
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Neuronal Signaling > GABA Receptors