GAL-021 sulfate is a potent BKCa-channel blocker that selectively inhibits KCa1.1 channels in GH3 cells. This compound serves as a novel modulator of breathing control, derived from selective modifications of the almitrine pharmacophore. Research indicates that GAL-021 sulfate effectively enhances minute ventilation in both rat and non-human primate models, making it relevant for studies in respiratory physiology and pharmacology.
GAL-021 sulfate is a potent BKCa-channel blocker that selectively inhibits KCa1.1 channels in GH3 cells. This compound serves as a novel modulator of breathing control, derived from selective modifications of the almitrine pharmacophore. Research indicates that GAL-021 sulfate effectively enhances minute ventilation in both rat and non-human primate models, making it relevant for studies in respiratory physiology and pharmacology.
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