Gatifloxacin

Catalog No.: A10419

DNA gyrase/topoisomerase IV inhibitor

Gatifloxacin Chemical Structure

CAS NO. 112811-59-3

Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC50 = 0.109 ng/ml) and topoisomerase IV (IC50 = 13.8 ng/ml).

Availability: In stock

Package Price Qty
100 mg
$40.00
1000 mg
$55.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC50 = 0.109 ng/ml) and topoisomerase IV (IC50 = 13.8 ng/ml).
Targets
DNA gyrase topoisomerase IV
In vitro DMSO 7 mg/mL (18.64 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.19 mL 266.39 mL
0.5 mM 5.33 mL 26.64 mL 53.28 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

*The above data is based on the productmolecular weight 375.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10419
Actions Inhibitor
M. Wt 375.39
Formula C19H22FN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 112811-59-3
Synonyms AM 1155?? AM1155?? AM-1155
SMILES CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

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