GBLD345

Catalog No.: A66923
GABAA Receptor PAM
GBLD345 is a potent positive allosteric modulator (PAM) of the GABAA receptor, functioning as a non-selective anxiolytic agent. This compound enhances GABAA receptor activity, leading to increased inhibitory neurotransmission. Its primary applications include research on anxiety disorders and studies investigating the role of GABAergic modulation in neural function.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGBLD345 is a potent positive allosteric modulator (PAM) of the GABAA receptor, functioning as a non-selective anxiolytic agent. This compound enhances GABAA receptor activity, leading to increased inhibitory neurotransmission. Its primary applications include research on anxiety disorders and studies investigating the role of GABAergic modulation in neural function.
Product Information
Catalog NumA66923
FormulaC21H21N5O2
Molecular Weight375.42
CAS Number122479-08-7
SMILESCOC1=CC(CNC2=NN3C(C=C2)=NC(C4=CC=C(N)C=C4)=C3OC)=CC=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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