Catalog No.: A10420

B-Raf inhibitor


GDC-0879 Chemical Structure

CAS NO. 905281-76-7

GDC-0879 is a specific inhibitor of B-Raf kinase enzyme,targeting B-Raf (V600E) (IC50: 0.13 nM).

Availability: In stock

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5 mg
10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Biological Activity

GDC-0879 is a specific inhibitor of B-Raf kinase enzyme,targeting B-Raf (V600E) (IC50: 0.13 nM).
B-Raf (A375, Colo205 cells)
0.13 nM
In vitro (25°C) DMSO Warmed: 65 mg/mL (194.39 mM)
Water Insoluble
Ethanol 5 mg/mL (14.95 mM)
In vivo 0.5% methylcellulose+0.2% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.9 mL 149.52 mL 299.04 mL
0.5 mM 5.98 mL 29.9 mL 59.81 mL
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10420
Actions Inhibitor
CAS No. 905281-76-7
Formula C19H18N4O2
M. Wt 334.4
Purity >98%
Synonyms GDC0879

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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