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Biological Activity
GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.67 mL | 108.34 mL | 216.68 mL |
| 0.5 mM | 4.33 mL | 21.67 mL | 43.34 mL |
| 1 mM | 2.17 mL | 10.83 mL | 21.67 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
*The above data is based on the productmolecular weight 461.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21507 |
|---|---|
| Actions | Degrader |
| CAS No. | 1443983-36-5 |
| Formula | C28H28FNO4 |
| M. Wt | 461.52 |
| Purity | >98% |
| Synonyms | SRN-927 Racemate, SRN 927, SRN927; GDC-0927, GDC 0927, |
| SMILES | OC1=CC=C2C(C(C)=C(C3=CC=CC(O)=C3)C(C4=CC=C(OCCN5CC(CF)C5)C=C4)O2)=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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