Gefitinib-d8 is a deuterium-labeled analogue of Gefitinib, a potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. With an IC50 ranging from 2 to 37 nM in NR6wtEGFR cells, this stable isotope serves as a valuable tool in quantitative analysis and metabolic studies. It is particularly useful for research applications involving drug metabolism and pharmacokinetics, enabling detailed investigations of EGFR-targeted therapies.
Gefitinib-d8 is a deuterium-labeled analogue of Gefitinib, a potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. With an IC50 ranging from 2 to 37 nM in NR6wtEGFR cells, this stable isotope serves as a valuable tool in quantitative analysis and metabolic studies. It is particularly useful for research applications involving drug metabolism and pharmacokinetics, enabling detailed investigations of EGFR-targeted therapies.
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