Gefitinib N-oxide is an N-oxide derivative of Gefitinib, acting as an inhibitor of the epidermal growth factor receptor (EGFR). It demonstrates a potent inhibitory effect, with an IC50 range of 2-37 nM in NR6wtEGFR cells. This compound is primarily utilized in research to investigate the modulation of EGFR signaling pathways and its implications in various cancer models.
Gefitinib N-oxide is an N-oxide derivative of Gefitinib, acting as an inhibitor of the epidermal growth factor receptor (EGFR). It demonstrates a potent inhibitory effect, with an IC50 range of 2-37 nM in NR6wtEGFR cells. This compound is primarily utilized in research to investigate the modulation of EGFR signaling pathways and its implications in various cancer models.
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