Gilteritinib-d8 is a deuterated form of Gilteritinib, a potent ATP-competitive inhibitor targeting FLT3 and AXL receptors, with IC50 values of 0.29 nM and 0.73 nM, respectively. This stable isotope is utilized in studies involving metabolic pathways, pharmacokinetics, and drug distribution in biological systems. Gilteritinib-d8 serves as an essential tool for researchers investigating FLT3/AXL-related signaling pathways and their implications in hematological malignancies.
Gilteritinib-d8 is a deuterated form of Gilteritinib, a potent ATP-competitive inhibitor targeting FLT3 and AXL receptors, with IC50 values of 0.29 nM and 0.73 nM, respectively. This stable isotope is utilized in studies involving metabolic pathways, pharmacokinetics, and drug distribution in biological systems. Gilteritinib-d8 serves as an essential tool for researchers investigating FLT3/AXL-related signaling pathways and their implications in hematological malignancies.
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