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Glimepiride

Catalog No.: A10430

Kir6.2/SUR inhibitor

Glimepiride

Glimepiride Chemical Structure

CAS NO. 93479-97-1

Glimepiride is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.

Availability: In stock

Package Price Qty
500 mg
$60.00
1000 mg
$100.00
2000 mg
$180.00
5000 mg
$400.00
10mM * 1mL in DMSO
$60.00
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Biological Activity

Glimepiride is a potent Kir6.2/SUR inhibitor with IC50 of 3.0 nM, 5.4 nM, and 7.3 nM for SUR1, SUR2A and SUR2B, used in the treatment of type 2 diabetes mellitus.
Targets
SUR1 SUR2A SUR2B
3 nM5.4 nM7.3 nM
In vitro DMSO 10 mg/mL (20.38 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.38 mL 101.91 mL 203.82 mL
0.5 mM 4.08 mL 20.38 mL 40.76 mL
1 mM 2.04 mL 10.19 mL 20.38 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 490.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10430
Actions Inhibitor
CAS No. 93479-97-1
Formula C24H34N4O5S
M. Wt 490.62
Purity >98%
Synonyms Amary
SMILES CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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