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Glutarimide-Isoindolinone-NH-PEG4-COOH

Catalog No.: A80045
E3 Ligase Ligand-Linker Conjugates
Glutarimide-Isoindolinone-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound features a cereblon ligand that facilitates the recruitment of E3 ligases, promoting ubiquitination of target proteins. Its unique PEG4 linker enhances solubility and stability, making it suitable for use in PROTAC technology and related research endeavors in protein regulation and therapeutic development.
Glutarimide-Isoindolinone-NH-PEG4-COOH 2927334-86-7 E3 Ligase Ligand-Linker Conjugates
Grouped product items
Size Price Stock Qty
5mg
$205.00
In stock
10mg
$330.00
In stock
25mg
$665.00
In stock
50mg
$965.00
In stock
100mg
$1,600.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGlutarimide-Isoindolinone-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound features a cereblon ligand that facilitates the recruitment of E3 ligases, promoting ubiquitination of target proteins. Its unique PEG4 linker enhances solubility and stability, making it suitable for use in PROTAC technology and related research endeavors in protein regulation and therapeutic development.
Product Information
Catalog NumA80045
FormulaC24H33N3O9
Molecular Weight507.53
CAS Number2927334-86-7
SMILESO=C1C2=CC=C(C=C2CN1C3C(NC(CC3)=O)=O)NCCOCCOCCOCCOCCC(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PROTAC > E3 Ligase Ligand-Linker Conjugate