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Glyco-Obeticholic acid

Catalog No.: A74879
FXR Agonist
Glyco-Obeticholic acid is an active metabolite of Obeticholic acid and acts as a farnesoid X receptor (FXR) agonist. By activating FXR, it plays a vital role in regulating bile acid homeostasis, lipid metabolism, and glucose metabolism. This compound is primarily used in research to investigate metabolic disorders, liver diseases, and potential therapeutic strategies for cholestatic liver conditions.
Glyco-Obeticholic acid 863239-60-5 FXR Agonist
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
2mg
$55.00
In stock
5mg
$95.00
In stock
10mg
$145.00
In stock
25mg
$290.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGlyco-Obeticholic acid is an active metabolite of Obeticholic acid and acts as a farnesoid X receptor (FXR) agonist. By activating FXR, it plays a vital role in regulating bile acid homeostasis, lipid metabolism, and glucose metabolism. This compound is primarily used in research to investigate metabolic disorders, liver diseases, and potential therapeutic strategies for cholestatic liver conditions.
Product Information
Catalog NumA74879
FormulaC28H47NO5
Molecular Weight477.68
CAS Number863239-60-5
SMILESO=C(O)CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Metabolism > FXR