Glyphosate-13C is a stable isotope-labeled form of glyphosate, a non-selective systemic herbicide that targets the 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) within the shikimic acid pathway. By inhibiting EPSPS, glyphosate effectively disrupts the synthesis of key aromatic amino acids, including tyrosine, phenylalanine, and tryptophan. Its biological activity includes the induction of oxidative stress and neuroinflammation, which can lead to mitochondrial dysfunction and neuronal cell death through autophagy or apoptosis. This compound is useful in research applications related to herbicide metabolism, environmental impact studies, and understanding the neurotoxic effects associated with glyphosate exposure.
Glyphosate-13C is a stable isotope-labeled form of glyphosate, a non-selective systemic herbicide that targets the 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) within the shikimic acid pathway. By inhibiting EPSPS, glyphosate effectively disrupts the synthesis of key aromatic amino acids, including tyrosine, phenylalanine, and tryptophan. Its biological activity includes the induction of oxidative stress and neuroinflammation, which can lead to mitochondrial dysfunction and neuronal cell death through autophagy or apoptosis. This compound is useful in research applications related to herbicide metabolism, environmental impact studies, and understanding the neurotoxic effects associated with glyphosate exposure.
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