GNE-616

Name: GNE-616
SKU: A19046
Price: 350 USD
Rating: 5 (288 reviews)

Catalog No.: A19046

Nav1.7 inhibitor

GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1.7 inhibitor (Ki of 0.79 nM and Kd of 0.38 nM for hNav1.7) for the treatment of chronic pain.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Notify me when the price drops

Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Contact your local distributors

Not your Region? View all Distributors

Adooq Products cited in reputable paper

Biological Activity

Discription

GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1.7 inhibitor (Ki of 0.79 nM and Kd of 0.38 nM for hNav1.7) for the treatment of chronic pain.

Targets

Target	Value

Chemical Information

Catalog Num	A19046
Formula	C24H23F4N5O3S
Molecular Weight	537.53
CAS Number	2349371-81-7
SMILES	O=S(C1=C(F)C=C2[C@@H](N3[C@@H](C4=NC=CC=C4)C[C@@H](C(F)(F)F)CC3)CCOC2=C1)(NC5=NC=NC=C5)=O
Synonyms	GNE 616, GNE616
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
GNE-616 5mg	$350.00	In stock
GNE-616 10mg	$650.00	In stock
GNE-616 50mg	$2,000.00	In stock