GNE-616

Catalog No.: A19046
Nav1.7 inhibitor
GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1.7 inhibitor (Ki of 0.79 nM and Kd of 0.38 nM for hNav1.7) for the treatment of chronic pain.
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Product Name Price Stock Qty
GNE-616 5mg
Special Price $280.00 Regular Price $350.00
In stock
GNE-616 10mg
Special Price $520.00 Regular Price $650.00
In stock
GNE-616 50mg
Special Price $1,600.00 Regular Price $2,000.00
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Biological Activity
Discription GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1.7 inhibitor (Ki of 0.79 nM and Kd of 0.38 nM for hNav1.7) for the treatment of chronic pain.
Targets
Target Value
Product Information
Catalog Num A19046
Formula C24H23F4N5O3S
Molecular Weight 537.53
CAS Number 2349371-81-7
SMILES O=S(C1=C(F)C=C2[C@@H](N3[C@@H](C4=NC=CC=C4)C[C@@H](C(F)(F)F)CC3)CCOC2=C1)(NC5=NC=NC=C5)=O
Synonyms GNE 616, GNE616
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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