GNE0877

Catalog No.: A13969

LRRK2 inhibitor

GNE0877

GNE0877 Chemical Structure

CAS NO. 1374828-69-9

GNE-0877 is a highly potent and selective LRRK2 inhibitor.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$280.00
25 mg
$550.00
10mM * 1mL in DMSO
$195.00
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Biological Activity

GNE-0877 is a highly potent and selective LRRK2 inhibitor.
Targets
LRRK2
0.7 nM(Ki)
In vitro DMSO 63 mg/mL (185.66 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.47 mL 147.35 mL 294.71 mL
0.5 mM 5.89 mL 29.47 mL 58.94 mL
1 mM 2.95 mL 14.74 mL 29.47 mL
5 mM 0.59 mL 2.95 mL 5.89 mL

*The above data is based on the productmolecular weight 339.31895. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13969
Actions Inhibitor
CAS No. 1374828-69-9
Formula C14H16F3N7
M. Wt 339.31895
Purity >98%
Synonyms GNE-0877, GNE 0877, GNE0877
SMILES CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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