Catalog No.: A16849

Porcupine inhibitor


GNF-6231 Chemical Structure

CAS NO. 1243245-18-2

GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM.

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Biological Activity

GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM.
In vitro DMSO 87 mg/mL (193.98 mM)
Water Insoluble
Ethanol 5 mg/mL (11.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.49 mL 222.97 mL
0.5 mM 4.46 mL 22.3 mL 44.59 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16849
Actions Inhibitor
CAS No. 1243245-18-2
Formula C24H25FN6O2
M. Wt 448.49
Purity >98%
Synonyms GNF6231, GNF 6231

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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