GPR17 modulator-1 is a potent modulator of the G protein-coupled receptor GPR17, exhibiting an IC50 of less than 10 nM for human GPR17 in CHO cells. This compound demonstrates moderate pharmacokinetic properties in murine models and is capable of crossing the blood-brain barrier. GPR17 modulator-1 is valuable for research focused on neuroinflammatory disorders and central nervous system-related applications.
GPR17 modulator-1 is a potent modulator of the G protein-coupled receptor GPR17, exhibiting an IC50 of less than 10 nM for human GPR17 in CHO cells. This compound demonstrates moderate pharmacokinetic properties in murine models and is capable of crossing the blood-brain barrier. GPR17 modulator-1 is valuable for research focused on neuroinflammatory disorders and central nervous system-related applications.
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