GPR35 Agonist 4 is a selective activator of the GPR35 receptor, exhibiting a potency with an pEC50 value of 5.86. This compound demonstrates significant biological activity in both human and rat models, making it a valuable tool for studying GPR35 signaling pathways. Notably, mutation of the arginine at position 3.36 negates the agonistic effect of GPR35 Agonist 4, underscoring its mechanism of action. This reagent can be utilized in pharmacological research investigating the role of GPR35 in various physiological and pathological processes.
GPR35 Agonist 4 is a selective activator of the GPR35 receptor, exhibiting a potency with an pEC50 value of 5.86. This compound demonstrates significant biological activity in both human and rat models, making it a valuable tool for studying GPR35 signaling pathways. Notably, mutation of the arginine at position 3.36 negates the agonistic effect of GPR35 Agonist 4, underscoring its mechanism of action. This reagent can be utilized in pharmacological research investigating the role of GPR35 in various physiological and pathological processes.
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