GPR6 inverse agonist 1

Catalog No.: A60832
GPR6 Inverse Agonist
GPR6 inverse agonist 1 is a selective inverse agonist for the GPR6 receptor, demonstrating an IC50 of less than 100 nM. This compound is essential for research investigating the pathological mechanisms of neurodegenerative disorders, particularly Parkinson's disease and Huntington's disease. Its ability to modulate GPR6 activity makes it a valuable tool for studying these conditions and exploring potential therapeutic strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionGPR6 inverse agonist 1 is a selective inverse agonist for the GPR6 receptor, demonstrating an IC50 of less than 100 nM. This compound is essential for research investigating the pathological mechanisms of neurodegenerative disorders, particularly Parkinson's disease and Huntington's disease. Its ability to modulate GPR6 activity makes it a valuable tool for studying these conditions and exploring potential therapeutic strategies.
Product Information
Catalog NumA60832
FormulaC25H32F2N6O2
Molecular Weight486.56
CAS Number3095588-50-1
SMILESFC1=C(CN2CCN(C3=C(NC(C)C)N=C(C=NC(C(O)C(O)(C)C)=C4)C4=N3)CC2)C=CC(F)=C1
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