GPR84 antagonist 2 is a selective oral antagonist of the GPR84 receptor, exhibiting an IC50 of 8.95 nM. It demonstrates enhanced potency in calcium mobilization assays and effectively inhibits the chemotaxis of neutrophils and macrophages activated by GPR84. This compound is valuable for research into conditions such as ulcerative colitis, providing insights into immune regulation and inflammation.
GPR84 antagonist 2 is a selective oral antagonist of the GPR84 receptor, exhibiting an IC50 of 8.95 nM. It demonstrates enhanced potency in calcium mobilization assays and effectively inhibits the chemotaxis of neutrophils and macrophages activated by GPR84. This compound is valuable for research into conditions such as ulcerative colitis, providing insights into immune regulation and inflammation.
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