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GSK 2334470


PDK1 Inhibitor

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Catalog No. A12767

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK 2334470 10mg A12767-10

Regular Price: €85.50

Special Price: €76.95

GSK 2334470 25mg A12767-25

Regular Price: €171.00

Special Price: €153.90

GSK 2334470 50mg A12767-50

Regular Price: €285.00

Special Price: €256.50

GSK 2334470 100mg A12767-100

Regular Price: €475.00

Special Price: €427.50

GSK 2334470 10mM * 1mL in DMSO A12767-10mM-D

Regular Price: €95.95

Special Price: €86.36

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).

GSK 2334470

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Chemical Information

Catalog Num A12767
Actions Inhibitor
M. Wt 462.59
Formula C25H34N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227911-45-6
Synonyms GSK-2334470, GSK2334470
SMILES C[[email protected]@H]1CC[[email protected]@H](CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5

Biological Activity

GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
PDK-1 (Cell-free assay)
10 nM


Solubility (25°C)* In vitro DMSO 90 mg/mL (194.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol 90 mg/mL (194.55 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.09 mL 216.17mL
0.5 mM 4.32 mL 21.62 mL 43.23 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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