GSK J1
GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX
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Adooq Products cited in reputable paper
Adooq's GSK J1 has been cited by 2 publications
Biological Activity
| Discription | GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX | ||
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Product Information
| Catalog Num | A12918 |
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| Formula | C22H23N5O2 |
| Molecular Weight | 389.45 |
| CAS Number | 1373422-53-7 |
| SMILES | C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CC=CC=N4)NCCC(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 70 mg/mL (179.74 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.68 mL | 128.39 mL | 256.77 mL |
| 0.5 mM | 5.14 mL | 25.68 mL | 51.35 mL |
| 1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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