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GSK J1

Catalog No.: A12918
Histone demethylase inhibitor
Adooq's GSK J1 has been cited by 2 publications
GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX
GSK J1
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$55.00
In stock
25mg
$90.00
In stock
50mg
$170.00
In stock
100mg
$305.00
In stock
10mM * 1mL in DMSO
$60.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GSK J1 has been cited by 2 publications
  • Nicolas A Fraunhoffer, .et al. , EBioMedicine, 2023, Jun;92:104602 PMID: 37148583
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
    • Biological Activity
    Discription GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A12918
    Formula C22H23N5O2
    Molecular Weight 389.45
    CAS Number 1373422-53-7
    SMILES C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CC=CC=N4)NCCC(=O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO 70 mg/mL (179.74 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.68 mL 128.39 mL 256.77 mL
    0.5 mM 5.14 mL 25.68 mL 51.35 mL
    1 mM 2.57 mL 12.84 mL 25.68 mL
    5 mM 0.51 mL 2.57 mL 5.14 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Epigenetics > Histone Demethylases
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