GSK J1

Catalog No.: A12918

Histone demethylase inhibitor

GSK J1

GSK J1 Chemical Structure

CAS NO. 1373422-53-7

GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $130.00

Special Price $117.00

50 mg

Regular Price: $230.00

Special Price $207.00

100 mg

Regular Price: $380.00

Special Price $342.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX
Targets
JMJD3 (KDM6B) UTX (KDM6A)
28 nM53 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.68 mL 128.39 mL 256.77 mL
0.5 mM 5.14 mL 25.68 mL 51.35 mL
1 mM 2.57 mL 12.84 mL 25.68 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 389.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12918
Actions Inhibitor
M. Wt 389.45
Formula C22H23N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1373422-53-7
Synonyms 0
SMILES C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CC=CC=N4)NCCC(=O)O

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