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GSK163090

5-HT1A/B/D receptor antagonist

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Catalog No. A15838

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GSK163090 5mg A15838-5
$220.00
GSK163090 10mg A15838-10
$400.00
GSK163090 25mg A15838-25
$800.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively.

GSK163090

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Chemical Information

Catalog Num A15838
Actions Antagonist
M. Wt 415.53
Formula C25H29N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 844903-58-8
Synonyms GSK-163090, GSK 163090
SMILES CC1=NC2=C(C=C1)C(=CC=C2)N3CCN(CC3)CCC4=CC(=CC=C4)N5CCNC5=O

Biological Activity

Description
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.33 mL 240.66mL
0.5 mM 4.81 mL 24.07 mL 48.13 mL
1 mM 2.41 mL 12.03 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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