GSK1795091

Catalog No.: A35330
TLR4 Agonist
GSK1795091 is a synthetic TLR4 agonist that serves as a potent immunologic stimulator. It demonstrates significant antitumor activity by inhibiting tumor growth and enhancing survival in murine models. Additionally, GSK1795091 acts as an effective vaccine adjuvant, improving both mucosal and systemic immune responses to influenza virus vaccines, and has been shown to promote long-term survival in influenza challenge models. This compound is valuable for research applications in immunology and cancer therapeutics.
Grouped product items
Size Price Stock Qty
1mg
$690.00
In stock
5mg
$1,765.00
In stock
10mg
$2,890.00
In stock
25mg
$5,460.00
In stock
50mg
$7,995.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGSK1795091 is a synthetic TLR4 agonist that serves as a potent immunologic stimulator. It demonstrates significant antitumor activity by inhibiting tumor growth and enhancing survival in murine models. Additionally, GSK1795091 acts as an effective vaccine adjuvant, improving both mucosal and systemic immune responses to influenza virus vaccines, and has been shown to promote long-term survival in influenza challenge models. This compound is valuable for research applications in immunology and cancer therapeutics.
Product Information
Catalog NumA35330
FormulaC81H157N2O16P
Molecular Weight1446.09
CAS Number1233589-81-5
SMILESO=C(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)O[C@@H]([C@@H]([C@H]1CO)O[P](O)(O)=O)[C@H]([C@@H](O1)OC[C@@H](C(O)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O
SynonymsCRX-601
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