GSK2194069

Catalog No.: A21827

hFAS inhibitor

GSK2194069

GSK2194069 Chemical Structure

CAS NO. 1332331-08-4

GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC50 of 7.7 ?? 4.1 nM in an assay detecting released CoA.

Availability: In stock

Package Price Qty
5 mg
$130.00
10 mg
$223.00
50 mg
$662.00
100 mg
$1,325.00
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Biological Activity

GSK2194069 is a potent and specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS with an IC50 of 7.7 ?? 4.1 nM in an assay detecting released CoA.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.69 mL 233.38 mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21827
Actions Inhibitor
CAS No. 1332331-08-4
Formula C25H24N4O3
M. Wt 428.48
Solubility DMSO
Purity >98%
Synonyms GSK 2194069, GSK-2194069
SMILES O=C(N1C[[email protected]](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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