GSK256073 tris

Catalog No.: A60774
GPR109A Agonist
GSK256073 tris is a selective and orally bioavailable agonist of GPR109A (HCA2), exhibiting a high potency with a pEC50 of 7.5 in human models. This compound acutely enhances glucose homeostasis through the inhibition of lipolysis, making it a valuable tool for research related to type 2 diabetes mellitus (T2DM) and dyslipidemia. Its long-lasting effect and non-flushing profile provide significant utility in metabolic disorder investigations.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGSK256073 tris is a selective and orally bioavailable agonist of GPR109A (HCA2), exhibiting a high potency with a pEC50 of 7.5 in human models. This compound acutely enhances glucose homeostasis through the inhibition of lipolysis, making it a valuable tool for research related to type 2 diabetes mellitus (T2DM) and dyslipidemia. Its long-lasting effect and non-flushing profile provide significant utility in metabolic disorder investigations.
Product Information
Catalog NumA60774
FormulaC14H24ClN5O5
Molecular Weight377.82
CAS Number1228650-42-7
SMILESO=C1NC(N(CCCCC)C2=C1NC(Cl)=N2)=O.OCC(CO)(CO)N
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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