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GSK2606414

Catalog No.: A12792
PERK inhibitor
Adooq's GSK2606414 has been cited by 3 publications
GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM.
GSK2606414
Grouped product items
Size Price Stock Qty
2mg
$55.00
In stock
5mg
$90.00
In stock
10mg
$120.00
In stock
25mg
$240.00
In stock
50mg
$380.00
In stock
100mg
$675.00
In stock
10mM * 1mL in DMSO
$90.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GSK2606414 has been cited by 3 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Linhao Xu, .et al. , Neural Plasticity, 2021, 23 Aug
  • Takashi Shimizu, .et al. , Sci Signal, 2021, Jan 26;14(667):eabb3616 PMID: 33500333
    • Biological Activity
    Discription GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A12792
    Formula C24H20F3N5O
    Molecular Weight 451.44
    CAS Number 1337531-36-8
    SMILES CN1C=C(C2=C1N=CN=C2N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
    Synonyms GSK-2606414, GSK 2606414
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 87 mg/mL (192.71 mM)
    Water Insoluble
    Ethanol 18 mg/mL (39.87 mM)
    In vivo 5% DMSO+45% PEG 300+ddH2O 19 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.15 mL 110.76 mL 221.51 mL
    0.5 mM 4.43 mL 22.15 mL 44.3 mL
    1 mM 2.22 mL 11.08 mL 22.15 mL
    5 mM 0.44 mL 2.22 mL 4.43 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Apoptosis > PERK
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