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GSK4394835A

Catalog No.: A42128
PDE3B Inhibitor
GSK4394835A is a reversible covalent inhibitor of phosphodiesterase 3B (PDE3B), exhibiting a pIC50 value of 6.2. This compound demonstrates significant efficacy in modulating cellular signaling pathways associated with cardiovascular diseases. GSK4394835A is a valuable tool for researchers investigating the role of PDE3B in cardiovascular disease mechanisms and potential therapeutic interventions.
GSK4394835A 3032458-06-0 PDE3B Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGSK4394835A is a reversible covalent inhibitor of phosphodiesterase 3B (PDE3B), exhibiting a pIC50 value of 6.2. This compound demonstrates significant efficacy in modulating cellular signaling pathways associated with cardiovascular diseases. GSK4394835A is a valuable tool for researchers investigating the role of PDE3B in cardiovascular disease mechanisms and potential therapeutic interventions.
Product Information
Catalog NumA42128
FormulaC27H26BN3O6
Molecular Weight499.32
CAS Number3032458-06-0
SMILESO=C(C1=CC(OC)=C2C=CC(OC)=CC2=N1)NC3=CC(C(N(CC4=CC=CC=C4)C)=O)=CC(B(O)O)=C3
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Metabolism > PDE