Guanfacine-d2 hydrochloride is a deuterated form of guanfacine hydrochloride, which primarily targets the α2A-adrenoceptor. This selective agonist exhibits a Kd of 31 nM, demonstrating significant selectivity with a 60-fold preference for the α2A subtype over the α2B receptor. This stable isotope-labeled compound is valuable for pharmacological studies and tracing applications in research related to hypertension and neuropharmacology.
Guanfacine-d2 hydrochloride is a deuterated form of guanfacine hydrochloride, which primarily targets the α2A-adrenoceptor. This selective agonist exhibits a Kd of 31 nM, demonstrating significant selectivity with a 60-fold preference for the α2A subtype over the α2B receptor. This stable isotope-labeled compound is valuable for pharmacological studies and tracing applications in research related to hypertension and neuropharmacology.
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