GW 5074

Catalog No.: A11436

Raf-1 Inhibitor

GW 5074

GW 5074 Chemical Structure

CAS NO. 220904-83-6

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor

Availability: In stock

Package Price Qty
10 mg
$80.00
25 mg
$120.00
50 mg
$160.00
100 mg
$190.00
10mM * 1mL in DMSO
$60.00
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Biological Activity

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
Targets
C-Raf
9 nM
In vitro (25°C) DMSO 101 mg/mL (193.87 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.2 mL 95.98 mL 191.96 mL
0.5 mM 3.84 mL 19.2 mL 38.39 mL
1 mM 1.92 mL 9.6 mL 19.2 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11436
Actions Inhibitor
CAS No. 220904-83-6
Formula C15H8Br2INO2
M. Wt 520.94
Purity >98%
Synonyms GW5074
SMILES C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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