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GW 5074


Raf-1 Inhibitor

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Catalog No. A11436

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GW 5074 10mg A11436-10

Regular Price: $80.00

Special Price: $72.00

GW 5074 25mg A11436-25

Regular Price: $120.00

Special Price: $108.00

GW 5074 50mg A11436-50

Regular Price: $160.00

Special Price: $144.00

GW 5074 100mg A11436-100

Regular Price: $190.00

Special Price: $171.00

GW 5074 10mM * 1mL in DMSO A11436-10mM-D

Regular Price: $60.00

Special Price: $54.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor

GW 5074

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Chemical Information

Catalog Num A11436
Actions Inhibitor
M. Wt 520.94
Formula C15H8Br2INO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 220904-83-6
Synonyms GW5074
SMILES C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2

Biological Activity

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
9 nM


Solubility (25°C) * In vitro DMSO 104 mg/mL (199.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.2 mL 95.98 mL 191.96mL
0.5 mM 3.84 mL 19.2 mL 38.39 mL
1 mM 1.92 mL 9.6 mL 19.2 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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