GW 5074

Catalog No.: A11436

Raf-1 Inhibitor

GW 5074

GW 5074 Chemical Structure

CAS NO. 220904-83-6

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $120.00

Special Price $108.00

50 mg

Regular Price: $160.00

Special Price $144.00

100 mg

Regular Price: $190.00

Special Price $171.00

10mM * 1mL in DMSO

Regular Price: $60.00

Special Price $54.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
Targets
C-Raf
9 nM
In vitro (25°C) DMSO 104 mg/mL (199.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.2 mL 95.98 mL 191.96 mL
0.5 mM 3.84 mL 19.2 mL 38.39 mL
1 mM 1.92 mL 9.6 mL 19.2 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11436
Actions Inhibitor
M. Wt 520.94
Formula C15H8Br2INO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 220904-83-6
Synonyms GW5074
SMILES C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2

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