GW 9578

Catalog No.: A39952
PPARα Agonist
GW 9578 is a selective agonist of the peroxisome proliferator-activated receptor alpha (PPARα), exhibiting EC50 values of 5 nM for murine PPARα and 50 nM for human PPARα. This compound demonstrates significant lipid-lowering activity, making it a valuable tool for research in metabolic disorders and cardiovascular diseases. GW 9578 may be utilized in studies investigating the role of PPARα activation in lipid metabolism and related therapeutic applications.
Grouped product items
Size Price Stock Qty
500µg
$85.00
In stock
1mg
$160.00
In stock
5mg
$670.00
In stock
10mg
$1,195.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGW 9578 is a selective agonist of the peroxisome proliferator-activated receptor alpha (PPARα), exhibiting EC50 values of 5 nM for murine PPARα and 50 nM for human PPARα. This compound demonstrates significant lipid-lowering activity, making it a valuable tool for research in metabolic disorders and cardiovascular diseases. GW 9578 may be utilized in studies investigating the role of PPARα activation in lipid metabolism and related therapeutic applications.
Product Information
Catalog NumA39952
FormulaC26H34F2N2O3S
Molecular Weight492.62
CAS Number247923-29-1
SMILESCC(C)(SC1=CC=C(CCN(C(NC2=CC=C(F)C=C2F)=O)CCCCCCC)C=C1)C(O)=O
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