GW3965 HCl

Catalog No.: A11204
LXR-like receptors agonist
GW3965 HCl is a selective and orally active liver X receptor (LXR) full agonist.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
5mg
$50.00
In stock
10mg
$85.00
In stock
25mg
$190.00
In stock
50mg
$370.00
In stock
100mg
$555.00
In stock
500mg
$1,225.00
In stock
10mM * 1mL in DMSO
$70.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Other Forms of GW3965 HCl

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Adooq's GW3965 HCl has been cited by 4 publications
  • Srustidhar Das, .et al. , Nature, 2025, Jan;637(8048):1198-1206 PMID: 39567700
  • Mohácsik P, .et al. , Endocrinology, 2018, Feb 1;159(2):1159-1171 PMID: 29253128
  • Pencheva N, .et al. , Cell., 2014, 156(5):986-1001 PMID: 24581497
  • Bin Dong, .et al. , J Lipid Res., 2013, May; 54(5): 1241-1254 PMID: 23427282
Biological Activity
DescriptionGW3965 HCl is a selective and orally active liver X receptor (LXR) full agonist.
Targets
TargetValue
Product Information
Catalog NumA11204
FormulaC33H31ClF3NO3.HCl
Molecular Weight618.51
CAS Number405911-17-3
SMILESC1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4.Cl
SynonymsGW-3965
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSOWarmed: 16 mg/mL (25.86 mM)
WaterInsoluble
EthanolInsoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM16.17 mL80.84 mL161.68 mL
0.5 mM3.23 mL16.17 mL32.34 mL
1 mM1.62 mL8.08 mL16.17 mL
5 mM0.32 mL1.62 mL3.23 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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