GW4064

Name: GW4064
SKU: A11141
Price: 60 USD
Rating: 5 (2 reviews)

Catalog No.: A11141

FXR agonist

Adooq's GW4064 has been cited by 2 publications

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).

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Grouped product items
Size	Price	Stock
10mg	$80.00	In stock
50mg	$250.00	In stock
100mg	$450.00	In stock
200mg	$850.00	In stock
*10mM 1mL in DMSO**	$60.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's GW4064 has been cited by 2 publications

Dong-Hyun Kim, .et al. , Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132

Takae K, .et al. , J Reprod Dev, 2018, Nov 16 PMID: 30449821

Biological Activity

Discription

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).

Targets

Target	Value

Product Information

Catalog Num	A11141
Formula	C28H22Cl3NO4
Molecular Weight	542.8
CAS Number	278779-30-9
SMILES	CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl
Synonyms	GW-4064
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	99 mg/mL (182.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.42 mL	92.11 mL	184.23 mL
0.5 mM	3.68 mL	18.42 mL	36.85 mL
1 mM	1.84 mL	9.21 mL	18.42 mL
5 mM	0.37 mL	1.84 mL	3.68 mL

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