Catalog No.: A11141

FXR agonist


GW4064 Chemical Structure

CAS NO. 278779-30-9

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $250.00

Special Price $200.00

100 mg

Regular Price: $450.00

Special Price $360.00

200 mg

Regular Price: $850.00

Special Price $680.00

10mM * 1mL in DMSO

Regular Price: $60.00

Special Price $48.00

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Takae K, .et al. Evidence for the involvement of FXR signaling in ovarian granulosa cell function, J Reprod Dev, 2018, Nov 16 PMID: 30449821

Biological Activity

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
65 nM(EC50)
In vitro (25°C) DMSO 99 mg/mL (182.37 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% methylcellulose 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.42 mL 92.11 mL 184.23 mL
0.5 mM 3.68 mL 18.42 mL 36.85 mL
1 mM 1.84 mL 9.21 mL 18.42 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 542.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11141
Actions Agonist
CAS No. 278779-30-9
Formula C28H22Cl3NO4
M. Wt 542.8
Purity >98%
Synonyms GW-4064
SMILES CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy GW4064 | GW4064 Supplier | purchase | cost | manufacturer | order | distributor | buy 278779-30-9| 278779-30-9 Supplier | purchase 278779-30-9 | 278779-30-9 cost | 278779-30-9 manufacturer | order 278779-30-9 | 278779-30-9 distributor