GW4064

Catalog No.: A11141
FXR agonist
GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
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Product Name Price Stock Qty
GW4064 10mg
Special Price $64.00 Regular Price $80.00
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GW4064 50mg
Special Price $200.00 Regular Price $250.00
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GW4064 100mg
Special Price $360.00 Regular Price $450.00
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GW4064 200mg
Special Price $680.00 Regular Price $850.00
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GW4064 10mM * 1mL in DMSO
Special Price $48.00 Regular Price $60.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GW4064 has been cited by 2 publications
  • Dong-Hyun Kim, .et al. , Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132
  • Takae K, .et al. , J Reprod Dev, 2018, Nov 16 PMID: 30449821
  • Biological Activity
    Discription GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A11141
    Formula C28H22Cl3NO4
    Molecular Weight 542.8
    CAS Number 278779-30-9
    SMILES CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl
    Synonyms GW-4064
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 99 mg/mL (182.37 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% methylcellulose 10 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.42 mL 92.11 mL 184.23 mL
    0.5 mM 3.68 mL 18.42 mL 36.85 mL
    1 mM 1.84 mL 9.21 mL 18.42 mL
    5 mM 0.37 mL 1.84 mL 3.68 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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