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$0.00 - Kanada F, .et al. Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract, Sci Rep, 2019, Dec 27;9(1):20085 PMID: 31882756
Biological Activity
GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.94 mL | 104.72 mL | 209.44 mL |
| 0.5 mM | 4.19 mL | 20.94 mL | 41.89 mL |
| 1 mM | 2.09 mL | 10.47 mL | 20.94 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11438 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 660868-91-7 |
| Formula | C22H18F3N3O4S |
| M. Wt | 477.46 |
| Purity | >98% |
| SMILES | COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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